A collaborative "THRIVE Fetus to Five" neonatal brain program review

Lina Chalak1, Margaret K Hoge2, June Hu2

  • 1UT Southwestern, Parkland and Childrens Health, Dallas, TX, USA. Lina.chalak@utsouthwestern.edu.

Pediatric Research
|January 4, 2026
PubMed

Insights

Specialized follow-up care for Neonatal Intensive Care Unit (NICU) graduates improves neurodevelopmental outcomes. Integrating multi-disciplinary primary care with specialty services ensures comprehensive support from infancy through adulthood.

Area of Science:

  • Neonatal care
  • Developmental pediatrics
  • Integrated healthcare models

Background:

  • Vulnerable infants post-Neonatal Intensive Care Unit (NICU) discharge require specialized monitoring for neurodevelopmental impairment and chronic conditions.
  • Advances in obstetric care enable earlier identification of high-risk fetuses, necessitating personalized interventions from prenatal stages through postnatal care.
  • Current follow-up often involves fragmented visits focused narrowly on neurodevelopment and growth.

Purpose of the Study:

  • To present the benefits of an integrated, multi-disciplinary primary care model for at-risk infants.
  • To describe a cohesive follow-up system combining primary care with specialty services for optimal infant outcomes.
  • To highlight a 'Fetus to Five' program prioritizing comprehensive and efficient care for infants' developmental trajectories.

Main Methods:

  • Embedding personalized medicine into a comprehensive, multi-disciplinary primary care framework.
  • Integrating specialty clinic services into a cohesive follow-up system.
  • Collaborative, multi-specialist approach across the infant's medical journey.

Main Results:

  • Significant benefits for at-risk infants through an integrated approach.
  • Maximized potential for optimal care and outcomes via cohesive, multi-disciplinary follow-up.
  • Efficient and comprehensive meeting of each child's needs, fostering thriving developmental outcomes and family satisfaction.

Conclusions:

  • Comprehensive, integrated care models significantly benefit Neonatal Intensive Care Unit (NICU) graduates.
  • Lifespan support for NICU graduates, extending into adolescence and adulthood, is crucial for sustained optimal health and developmental outcomes.
  • Expanding access to such integrated programs is key for the future of neonatal follow-up care.