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Generating LGE/CGE Organoids from Human Pluripotent Stem Cell-derived Brain Organoids Without External Signal

Xiaojin Zhu1, Zhile Bai1, Yuhan Ren1

  • 1Institute for Regenerative Medicine, State Key Laboratory of Cardiovascular Diseases and Medical Innovation Center, Shanghai East Hospital, School of Life Sciences and Technology, Tongji University, Shanghai 200092, China; Frontier Science Center for Stem Cell Research, Tongji University, Shanghai 200092, China.

Cell Reports
|January 4, 2026
PubMed

Keywords:
C-X-C chemokine receptor type 4CP: neuroscienceCP: stem cell researchCXCR4ESCsGABAergic neuronsLCOsLGE/CGELGE/CGE organoidsbrain organoidsembryonic stem cellsiPSCsinduced pluripotent stem cellslateral/caudal ganglionic eminence

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