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Updated: Jan 13, 2026

Synthesis and Purification of Iodoaziridines Involving Quantitative Selection of the Optimal Stationary Phase for Chromatography
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Published on: May 16, 2014

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Site-Selective Azidation of Arenes via Hypervalent Iodine-Mediated C-H Functionalization

Ziyang Zhang1, Jiajin Weng1, Yanchuan Zhao1

  • 1State Key Laboratory of Fluorine and Nitrogen Chemistry and Advanced Materials and Shanghai Hong Kong Joint Laboratory in Chemical Synthesis, Shanghai Institute of Organic Chemistry, University of the Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai 200032, China.

Organic Letters
|January 6, 2026
PubMed
Summary

This study introduces a new hypervalent iodine method for direct C-H azidation of arenes. This efficient process allows for late-stage functionalization of drug molecules and diverse compounds.

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