Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Matrix-Assisted Laser Desorption Ionization (MALDI)01:08

Matrix-Assisted Laser Desorption Ionization (MALDI)

949
Matrix-assisted laser desorption ionization (MALDI) is a powerful analytical technique used in mass spectrometry. It enables the identification and characterization of various biomolecules, including proteins, peptides, nucleic acids, and carbohydrates. MALDI is an ionization technique, widely employed in biological and medical research, as well as in fields like pharmacology and biochemistry.The analyte of interest, a biomolecule or a mixture of biomolecules, is mixed with a suitable matrix...
949
MALDI-TOF Mass Spectrometry01:19

MALDI-TOF Mass Spectrometry

6.5K
Mass spectrometry is a powerful characterization technique that can identify and separate a wide variety of compounds ranging from chemical to biological entities, based on their mass-to-charge ratio (m/z). The instruments that allow this detection, known as mass spectrometers, have three components: an ion source, a mass analyzer, and a detector. These spectrometers differ based on the nature of their ion source and analyzers.Matrix-assisted laser desorption ionization (MALDI) is a commonly...
6.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A dual-labeling fluorescent probe to track lysosomal polarity and endoplasmic reticulum dynamics during ferroptosis.

Chemical communications (Cambridge, England)·2024
Same author

Optimization of machine learning classification models for tumor cells based on cell elements heterogeneity with laser-induced breakdown spectroscopy.

Journal of biophotonics·2023
Same author

High-Throughput Recognition of Tumor Cells Using Label-Free Elemental Characteristics Based on Interpretable Deep Learning.

Analytical chemistry·2022
Same author

Ex vivo three-dimensional elemental imaging of mouse brain tissue block by laser-induced breakdown spectroscopy.

Journal of biophotonics·2021
Same author

Study on the Molecular Mechanisms Against Human Breast Cancer from Insight of Elemental Distribution in Tissue Based on Laser-Induced Breakdown Spectroscopy (LIBS).

Biological trace element research·2020
Same author

The Regulator Gene rnc Is Closely Involved in Biofilm Formation in Streptococcus mutans.

Caries research·2018
Same journal

Strain-Level Food Surveillance of <i>Escherichia coli</i> Using a Specific-Nonspecific Hybrid Sensor Array Strategy.

Analytical chemistry·2026
Same journal

A Field-Portable Fe(IV)-Mediated Competitive Quenching Chemiluminescence Platform with a Synchronous Y-Shaped Flow-through Cell for Broad-Spectrum Quantification of Volatile Phenols.

Analytical chemistry·2026
Same journal

Single-Molecule Characterization of CRISPR-Cas12a for Amplification-Free Genetic Testing.

Analytical chemistry·2026
Same journal

Integrated Acoustofluidic Manipulation and Oscillation-Stabilized Magnetic Relaxation Biosensing for <i>Salmonella</i> Detection.

Analytical chemistry·2026
Same journal

A Self-Powered Sensing Platform Based on the Janus Heterostructure for Machine Learning-Assisted Dual-Mode Detection of 17β-Estradiol.

Analytical chemistry·2026
Same journal

Large Language Model-Generated Dietary Metabolite Biomarker Database Drives Deep Annotation of the Human Diet Metabolome.

Analytical chemistry·2026
See all related articles

Related Experiment Video

Updated: Jan 13, 2026

Laser-induced Breakdown Spectroscopy: A New Approach for Nanoparticle's Mapping and Quantification in Organ Tissue
10:17

Laser-induced Breakdown Spectroscopy: A New Approach for Nanoparticle's Mapping and Quantification in Organ Tissue

Published on: June 18, 2014

14.2K

Multifiber Dimension-Conversion Laser-Induced Breakdown Spectroscopy (MFDC-LIBS): Real-Time Spatially Resolved LIBS

Ze Tian1, Yue Tang1, Weiheng Kong1

  • 1Research Center of Analytical Instrumentation, School of Mechanical Engineering, Sichuan University, Chengdu 610065, People's Republic of China.

Analytical Chemistry
|January 6, 2026
PubMed
Summary
This summary is machine-generated.

A new multifiber dimension-converting LIBS (MFDC-LIBS) system improves elemental analysis accuracy. This laser-induced breakdown spectroscopy method enhances quantitative precision for in situ compositional analysis of materials.

More Related Videos

Multiplex Chemical Imaging Based on Broadband Stimulated Raman Scattering Microscopy
09:57

Multiplex Chemical Imaging Based on Broadband Stimulated Raman Scattering Microscopy

Published on: July 25, 2022

4.5K
Quantitative Analysis of Vacuum Induction Melting by Laser-induced Breakdown Spectroscopy
03:49

Quantitative Analysis of Vacuum Induction Melting by Laser-induced Breakdown Spectroscopy

Published on: June 10, 2019

7.6K

Related Experiment Videos

Last Updated: Jan 13, 2026

Laser-induced Breakdown Spectroscopy: A New Approach for Nanoparticle's Mapping and Quantification in Organ Tissue
10:17

Laser-induced Breakdown Spectroscopy: A New Approach for Nanoparticle's Mapping and Quantification in Organ Tissue

Published on: June 18, 2014

14.2K
Multiplex Chemical Imaging Based on Broadband Stimulated Raman Scattering Microscopy
09:57

Multiplex Chemical Imaging Based on Broadband Stimulated Raman Scattering Microscopy

Published on: July 25, 2022

4.5K
Quantitative Analysis of Vacuum Induction Melting by Laser-induced Breakdown Spectroscopy
03:49

Quantitative Analysis of Vacuum Induction Melting by Laser-induced Breakdown Spectroscopy

Published on: June 10, 2019

7.6K

Area of Science:

  • Analytical Chemistry
  • Spectroscopy
  • Materials Science

Background:

  • Laser-induced breakdown spectroscopy (LIBS) offers rapid compositional analysis but struggles with accuracy due to uneven elemental distribution in plasma plumes.
  • In situ analysis is limited by the restricted accuracy and stability of conventional LIBS quantitative methods.

Purpose of the Study:

  • To develop a novel multifiber dimension-converting LIBS (MFDC-LIBS) system to address elemental distribution challenges.
  • To investigate the differentiated characterization of elemental distribution within a single plasma plume.
  • To enhance the accuracy and stability of LIBS quantitative analysis.

Main Methods:

  • Development of a proof-of-concept MFDC-LIBS system utilizing 100 optical fibers.
  • Simultaneous collection of 2D spatial distribution information from plasma plume.
  • Implementation of an array-to-linear transformation and spectral dispersion using a reflection grating.
  • Direct plasma image capture via an area-array CMOS detector.

Main Results:

  • The MFDC-LIBS system demonstrated significantly improved linearity, quantitative accuracy, and stability.
  • Root-mean-square error (RMSE) was reduced by 74% for Ca, 70% for Ba, 77% for Mg, and 66% for Na in rock samples.
  • Successful differentiation of elemental distribution within the plasma plume was achieved.

Conclusions:

  • The MFDC-LIBS system provides a robust and scalable approach for enhanced analytical precision in LIBS.
  • This method merges spatial diagnostics with improved quantitative capabilities for complex solid materials.
  • MFDC-LIBS overcomes limitations of conventional LIBS for accurate in situ compositional analysis.