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Fractures: Bone Repair

Fractures: Bone Repair

Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the...

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Related Experiment Video

Updated: Apr 30, 2026

Creating Rigidly Stabilized Fractures for Assessing Intramembranous Ossification, Distraction Osteogenesis, or Healing of Critical Sized Defects

Creating Rigidly Stabilized Fractures for Assessing Intramembranous Ossification, Distraction Osteogenesis, or Healing of Critical Sized Defects

Published on: April 11, 2012

Additively Manufactured 17-4 PH Stainless Steels for Fracture Management Devices.

Aruntapan Dash¹, Susmita Bose¹, Amit Bandyopadhyay¹

¹W. M. Keck Biomedical Materials Research Laboratory, School of Mechanical and Materials Engineering, Washington State University, Pullman, Washington, 99164, USA.

Virtual and Physical Prototyping

|January 7, 2026

Summary

This summary is machine-generated.

Magnetized 17-4PH stainless steel shows promise for fracture management, offering enhanced bone cell growth and significantly reduced bacterial colonization compared to traditional stainless steel 316L.

Keywords:

17-4PH 3D printing Additive manufacturing Pseudomonas aeruginosa (P. aeruginosa)Staphylococcus aureus (S. aureus)hFOB cell culture

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Fracture Apparatus Design and Protocol Optimization for Closed-stabilized Fractures in Rodents

Published on: August 14, 2018

Micromechanical Tension Testing of Additively Manufactured 17-4 PH Stainless Steel Specimens

Micromechanical Tension Testing of Additively Manufactured 17-4 PH Stainless Steel Specimens

Published on: April 7, 2021

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Last Updated: Apr 30, 2026

Creating Rigidly Stabilized Fractures for Assessing Intramembranous Ossification, Distraction Osteogenesis, or Healing of Critical Sized Defects

Creating Rigidly Stabilized Fractures for Assessing Intramembranous Ossification, Distraction Osteogenesis, or Healing of Critical Sized Defects

Published on: April 11, 2012

Fracture Apparatus Design and Protocol Optimization for Closed-stabilized Fractures in Rodents

Fracture Apparatus Design and Protocol Optimization for Closed-stabilized Fractures in Rodents

Published on: August 14, 2018

Micromechanical Tension Testing of Additively Manufactured 17-4 PH Stainless Steel Specimens

Micromechanical Tension Testing of Additively Manufactured 17-4 PH Stainless Steel Specimens

Published on: April 7, 2021

Area of Science:

Biomaterials Engineering
Orthopedic Materials Science
Medical Device Innovation

Background:

Stainless steel 316L (SS316L) is common in fracture devices but lacks antibacterial properties and can cause nickel-ion sensitivity.
17-4PH stainless steel presents a potential alternative with reduced nickel content and inherent antibacterial properties.
Laser-directed energy deposition (LDED) is a manufacturing method for producing these metallic implants.

Purpose of the Study:

To evaluate 17-4PH stainless steel as a superior alternative to SS316L for fracture management devices.
To investigate the effects of static magnetic field treatment on 17-4PH's biocompatibility and antibacterial efficacy.
To assess in vitro bone cell proliferation and bacterial inhibition on SS316L and 17-4PH.

Main Methods:

Manufacturing of SS316L and 17-4PH specimens using laser-directed energy deposition (LDED).
Compressive strength testing to compare mechanical properties.
In vitro studies involving human fetal osteoblast (hFOB) cell culture and bacterial inhibition assays with Staphylococcus aureus and Pseudomonas aeruginosa.
Application of a static magnetic field to 17-4PH specimens.

Main Results:

17-4PH specimens demonstrated over 150% greater compressive strength than SS316L.
Magnetized 17-4PH showed a 25% increase in human fetal osteoblast proliferation compared to SS316L.
Magnetized 17-4PH exhibited a 70% reduction in bacterial colonization by Staphylococcus aureus and Pseudomonas aeruginosa.

Conclusions:

Magnetized 17-4PH is a promising biomaterial for fracture management, offering improved mechanical strength and biocompatibility.
The material significantly enhances osteoblast proliferation and provides substantial bacterial resistance, addressing limitations of SS316L.
LDED manufacturing combined with magnetic treatment offers a novel approach for advanced orthopedic implant development.