Benefit of Influenza Vaccination in Patients with Cardiovascular Disease

Anshari Saifuddin Hasibuan1, Alvina Widhani2, Sukamto Koesnoe3

  • 11. Division of Allergy and Clinical Immunology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia. 2. Department of Internal Medicine, Universitas Indonesia Hospital, Depok, Jawa Barat, Indonesia. 3. Adult Immunization Task Force, Indonesian Society of Internal Medicine, Indonesia.. sorihsb@gmail.com.

Acta Medica Indonesiana
|January 8, 2026
PubMed

Insights

Influenza poses significant risks, especially for individuals with cardiovascular disease. Influenza vaccination is a proven, safe method to prevent infection and reduce major cardiovascular events in these vulnerable populations.

Area of Science:

  • Public Health
  • Cardiology
  • Infectious Diseases

Background:

  • Influenza is a major global health concern, with elevated risks for individuals with comorbidities like cardiovascular disease.
  • Cardiovascular disease is a leading cause of mortality worldwide and in Indonesia.
  • Seasonal influenza outbreaks are linked to increased cardiovascular events.

Purpose of the Study:

  • To review the impact of influenza on patients with cardiovascular disease.
  • To highlight the benefits of influenza vaccination in this high-risk group.

Main Methods:

  • This is a review article.
  • It synthesizes existing literature on influenza, cardiovascular disease, and vaccination.

Main Results:

  • Influenza vaccination is effective in preventing influenza infection.
  • Vaccination significantly reduces the risk of major cardiovascular events in individuals with cardiovascular disease.
  • Influenza vaccines are safe and well-tolerated in adults and the elderly.

Conclusions:

  • Influenza vaccination is a critical preventive measure for individuals with cardiovascular disease.
  • Vaccination mitigates both influenza complications and cardiovascular event risks.
  • Promoting influenza vaccination is essential for public health, particularly for vulnerable populations.

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