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[Analysis and Confirmation of the Ambiguous Results from HLA-DRB1 Genotyping Based on PacBio Sequencing]

Jie Liu1, Bing-Na Yang1, Zhan-Rou Quan1

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Zhongguo Shi Yan Xue Ye Xue Za Zhi
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PubMed
Summary

Next-generation sequencing (NGS) can produce ambiguous HLA-DRB1 genotyping results. Third-generation sequencing offers a reliable method to confirm novel or ambiguous alleles, ensuring accurate hematopoietic stem cell donor matching.

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