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Expansion of CKD diagnostics through biosensor technology: An early detection approach
Ganesh Pd Sahu1, Aniket Nandi1, Atanu Saha1
1Department of Pharmaceutical Chemistry and Analysis, ISF College of Pharmacy, Moga, Punjab 142001, India.
Clinica Chimica Acta; International Journal of Clinical Chemistry
|January 10, 2026
Summary
Early detection of chronic kidney disease (CKD) is crucial. Biosensor techniques offer a cost-effective and precise solution for identifying renal disease early, preventing severe complications and improving patient outcomes.
Area of Science:
- Nephrology
- Biomedical Engineering
- Diagnostic Technologies
Background:
- Chronic kidney disease (CKD) is a significant global health issue with high mortality rates, often progressing undetected due to asymptomatic early stages.
- Advanced CKD necessitates costly replacement therapies, highlighting the need for accessible diagnostic methods.
- Current CKD diagnostic tools are often expensive and not user-friendly, creating barriers to timely diagnosis.
Purpose of the Study:
- To systematically review advancements in CKD detection over the past decade (2015-2025).
- To explore complications associated with CKD and compare traditional diagnostic methods with modern approaches.
- To highlight the potential of biosensor-based techniques for early and accurate CKD diagnosis.
Main Methods:
- Comprehensive literature review of studies published between 2015 and 2025.
- Analysis of CKD complications, traditional diagnostic techniques, and emerging biomarkers.
- Categorization and evaluation of various biosensor types, including electrochemical, optical, fluorescent/colorimetric, and AI-assisted biosensors.
Main Results:
- Biosensors present a promising, cost-effective, and precise alternative for early CKD detection.
- Recent biomarkers and advanced biosensor technologies show significant potential for improved diagnostic capabilities.
- AI-assisted biosensors represent a cutting-edge development in enhancing diagnostic accuracy and efficiency.
Conclusions:
- Early detection of CKD via biosensors can significantly reduce patient burden and prevent severe renal complications.
- Biosensor technology offers a user-friendly and affordable approach to widespread CKD screening.
- Continued research and development in biosensors are vital for combating the global impact of chronic kidney disease.
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