Triboelectric Wearable Devices for Wound Healing: Materials, Mechanisms, and Innovative Designs

Area of Science:

• Biomaterials Science
• Regenerative Medicine
• Wearable Technology

Background:

• Wound healing faces challenges like infection and chronic non-healing.
• Traditional electrical stimulation (ES) has limitations: external power, rigid electrodes, and lack of feedback.
• Triboelectric Nanogenerators (TENGs) offer a novel approach to intelligent wound management.

Purpose of the Study:

• To systematically review recent advancements in triboelectric wearable devices for intelligent wound management.
• To summarize material types, structural designs, and mechanisms of TENGs in wound healing.
• To explore clinical applications and future research directions for TENG-based wound care.

Main Methods:

• Review of triboelectric materials and electrode designs for TENGs.
• Elucidation of mechanisms by which TENGs promote cell proliferation, migration, and angiogenesis.
• Exploration of TENG applications in combination therapies and diagnostic platforms.

Main Results:

• Triboelectric wearable devices show promise in overcoming ES limitations.
• TENGs facilitate key biological processes essential for wound healing.
• Innovative applications include integrated diagnostics and combination treatments.

Conclusions:

• Triboelectric wearable devices represent a significant advancement in intelligent wound management.
• Further research is needed on material stability, device integration, and scalability for clinical translation.
• TENGs offer a promising future for optimizing wound healing therapies.