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Updated: Jan 24, 2026
09:09
Treatment with Vancomycin Loaded Calcium Sulphate and Autogenous Bone in an Improved Rabbit Model of Bone Infection
Published on: March 14, 2019
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Current Management of Serious Infections due to Vancomycin-resistant Enterococci.
Sara I Gomez-Villegas1, William R Miller2, Cesar A Arias2
1Division of Infectious Diseases, Department of Medicine, Houston Methodist Hospital, Houston, Texas, USA; Center for Infectious Diseases, Houston Methodist Research Institute, Houston, Texas, USA.
Infectious Disease Clinics of North America
|January 22, 2026
Summary
Vancomycin-resistant enterococci (VRE) pose significant challenges in healthcare settings. This review examines current and emerging treatments for serious VRE infections like bacteremia and endocarditis.
Area of Science:
- Infectious Diseases
- Clinical Microbiology
- Pharmacology
Background:
- Vancomycin-resistant enterococci (VRE) are critical healthcare-associated pathogens.
- VRE infections lead to substantial patient morbidity and mortality, especially in vulnerable populations.
- Managing VRE infections is difficult due to limited treatment options and scarce clinical evidence.
Purpose of the Study:
- To review current evidence on treating serious VRE infections.
- To discuss emerging therapeutic strategies for VRE.
- To highlight the impact of delayed therapy on VRE bloodstream infections.
Main Methods:
- Literature review of clinical studies and evidence.
- Synthesis of data on established treatment protocols.
- Identification and summary of novel treatment approaches.
Main Results:
- Treatment of VRE infections is complex and requires careful consideration of available agents.
- Timely initiation of effective therapy is crucial for improving outcomes in VRE bacteremia.
- Several novel agents and strategies are under investigation for VRE infections.
Conclusions:
- Effective management of VRE infections necessitates a thorough understanding of current evidence and emerging options.
- Further research is needed to establish optimal treatment regimens for VRE.
- Addressing VRE requires a multi-faceted approach including infection control and therapeutic innovation.
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