Power Duo against Sensitivity: Ozone and Toothpaste Synergy - A Randomized Controlled Trial.

Area of Science:

• Dentistry
• Oral Health
• Regenerative Medicine

Background:

• Dentinal hypersensitivity (DH) causes sharp pain from stimuli, often inadequately managed by conventional treatments.
• This study investigates a novel approach to DH management by combining ozone therapy with desensitizing toothpaste.

Purpose of the Study:

• To evaluate the efficacy of combined ozone therapy and desensitizing toothpaste versus toothpaste alone for managing dentinal hypersensitivity.
• To assess the long-term effectiveness and safety of this combined treatment approach.

Main Methods:

• A randomized controlled trial involved 80 patients with moderate-to-severe DH.
• The test group received ozone therapy plus desensitizing toothpaste; the control group received 5% potassium nitrate toothpaste.
• Sensitivity was measured using VAS, Air Blast Test, and SCASS, with SEM for tubule occlusion analysis over 6 months.

Main Results:

• Both groups experienced significant sensitivity reduction, but the test group showed substantially greater VAS and SCASS score decreases.
• The benefits in the test group were sustained for 6 months, unlike the control group's plateaued results.
• No adverse effects were reported for either treatment group.

Conclusions:

• Ozone therapy combined with desensitizing toothpaste provides superior and long-lasting relief for dentinal hypersensitivity.
• The treatment's antimicrobial, anti-inflammatory, and remineralizing properties aid dentinal repair and enhance patient comfort.
• This combination therapy is a safe and effective adjunct to standard dental care for DH.