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TREAT-AIS: A Multicenter National Registry.

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Summary
This summary is machine-generated.

The Taiwan Registry of Endovascular Thrombectomy for Acute Ischemic Stroke (TREAT-AIS) collected data on 1522 patients. While men showed higher functional independence post-EVT initially, this difference was not significant after adjusting for key factors.

Keywords:
ischemic strokeregistrysexthrombectomy

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Area of Science:

  • Neurology
  • Cardiovascular Diseases
  • Public Health

Background:

  • Endovascular thrombectomy (EVT) is the standard treatment for acute ischemic stroke due to large-artery occlusion.
  • The Taiwan Stroke Society initiated the nationwide TREAT-AIS registry in January 2019 to track EVT outcomes.
  • This registry captures real-world data on EVT procedures and patient outcomes in Taiwan.

Purpose of the Study:

  • To present the study design, progress, and baseline data of the TREAT-AIS registry.
  • To analyze the effectiveness of EVT in achieving functional independence at 3 months post-stroke.
  • To investigate the influence of sex on post-EVT outcomes in acute ischemic stroke patients.

Main Methods:

  • A multicenter prospective registration program involving patients aged 20 years or older undergoing EVT for acute ischemic stroke.
  • Data collection included general stroke demographics and EVT-specific details.
  • Functional independence (modified Rankin Scale score 0-2) at 3 months was the primary effectiveness outcome; sex differences were analyzed.

Main Results:

  • 1522 patients were enrolled by June 2022 across 19 medical centers.
  • The median NIH Stroke Scale score was 18; cardioembolism was the most common stroke cause (43.6%).
  • Functional independence was achieved in 36.2% of patients; initial male advantage diminished after adjusting for age, stroke severity, and recanalization.

Conclusions:

  • The TREAT-AIS registry is effectively capturing real-world EVT data in Taiwan.
  • The registry provides valuable insights into EVT practices and quality of care for acute stroke patients in an Asian population.
  • Further analysis will elucidate factors influencing EVT outcomes in this cohort.