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Updated: Jan 28, 2026

Author Spotlight: Advancing Allergic Rhinitis Research with Multicolor Immunofluorescence
Published on: September 22, 2023
[Research status and hotspots of seasonal allergic rhinitis based on CiteSpace visualization analysis]
Hexiao Tian1, Dongdong Zhu1, Boning Zhao1
1Department of Otorhinolaryngology Head and Neck Surgery,China-Japan Union Hospital of Jilin University,Changchun,130033,China.
Abstract:
Objective:To analyze the current status, hotspots, and development trends of research in the field of seasonal allergic rhinitis(SAR) using bibliometric methods, providing references for clinical diagnosis and treatment and research directions. Methods:Based on SAR-related literature from the Web of Science Core Collection(WoSCC) database from 2014 to 2024, CiteSpace 6.4. R1 software was used to construct national/institutional collaboration networks, keyword co-occurrence, and emergent maps, combined with cluster analysis to explore the evolution of research hotspots. Results:A total of 1 037 articles were identified; annual output peaked in 2021. The most productive countries were the United States (241 articles), Germany (146), and China (135). Institutions in Berlin showed the tightest collaborative ties.The core prolific authors include Ludger Klimek, Stephen R. Durham, and Luo Zhang, and their teams. High-frequency keywords included "asthma", "double-blind trial", and "efficacy". Cluster analysis indicated that systematic reviews and immunotherapy dominated the past eleven years. Since 2019, cross-reactivity, birch pollen, food allergy, and pollen allergy have emerged as new frontiers. Conclusion:SAR research is shifting from empirical therapy validation to precision medicine. Deciphering cross-reactivity mechanisms and expanding biological agents will be central to future work. Although China's scholarly output has grown markedly, stronger transnational collaboration is still warranted. Systematic reviews, molecular diagnostics, and targeted therapies are expected to optimize SAR management strategies.
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