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Microsporidium Keratitis After Hurricane Francine: A Case Report
Zachary A Dwyer1, Stephen V Lau2
1Kirksville College of Osteopathic Medicine, A.T. Still University, Kirksville, Missouri, USA, atsu.edu.
Case Reports in Ophthalmological Medicine
|January 29, 2026
Summary
Microsporidial ocular infections, often linked to contaminated water, are rising. This report details five pediatric cases of microsporidial keratoconjunctivitis following a hurricane, successfully treated with moxifloxacin and fluorometholone.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Microbiology
Background:
- Microsporidial ocular infections are increasingly prevalent, particularly in temperate regions.
- A cluster of five cases of microsporidial keratoconjunctivitis occurred in Southeastern Louisiana.
- These cases presented within three months following Hurricane Francine.
Purpose of the Study:
- To report a case series of microsporidial keratoconjunctivitis.
- To describe the clinical features and management of these infections.
- To highlight the association with environmental exposure post-hurricane.
Main Methods:
- Case report of five patients (ages 5-23) presenting with ocular symptoms.
- Clinical diagnosis of microsporidial keratoconjunctivitis based on typical features.
- Polymerase Chain Reaction (PCR) used for microsporidia detection in all patients.
Main Results:
- All five patients were diagnosed with microsporidial keratoconjunctivitis.
- Four out of five patients reported exposure to contaminated water.
- PCR confirmed microsporidia in all affected individuals.
- Effective treatment was achieved with moxifloxacin and fluorometholone.
Conclusions:
- Microsporidial keratoconjunctivitis can present as a post-disaster outbreak.
- Contaminated water is a likely source of infection.
- A combination of moxifloxacin and fluorometholone provides an effective treatment strategy.
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