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Cellulose and cellulose-based materials for enzyme immobilization: a review
Maria S Lavlinskaya1, Andrey V Sorokin1, Marina G Holyavka1
1Biophysics and Biotechnology Department, Voronezh State University, 1 Universitetskaya Ploshchad, Voronezh, 394018 Russia.
Biophysical Reviews
|January 30, 2026
Summary
Enzyme immobilization on cellulose enhances enzyme reusability and stability. This review covers over 200 studies on cellulose-based enzyme supports, highlighting their impact on enzymatic performance for green chemistry applications.
Area of Science:
- Biocatalysis
- Green Chemistry
- Materials Science
Background:
- Enzymes are efficient natural catalysts valuable in green chemistry.
- Enzyme immobilization on supports like cellulose improves reusability and operational stability.
- Cellulose is a cost-effective, low-toxicity biopolymer suitable for enzyme applications.
Purpose of the Study:
- To review recent advancements in enzyme immobilization on cellulose and its derivatives.
- To emphasize the impact of cellulose-based immobilization on enzyme activity and performance.
- To highlight the potential of these systems in food and biomedical technologies.
Main Methods:
- Literature review of over 200 studies from the past decade.
- Analysis of enzyme immobilization techniques on various cellulose forms.
- Evaluation of reported changes in enzymatic activity, stability, and reusability.
Main Results:
- Cellulose-based enzyme immobilization consistently enhances enzyme stability and reusability.
- Immobilization on cellulose derivatives offers tailored properties for specific applications.
- Optimized enzyme-cellulose systems demonstrate improved catalytic efficiency.
Conclusions:
- Enzyme immobilization on cellulose is a key strategy for developing robust biocatalysts.
- Cellulose-derived supports are promising for sustainable enzymatic technologies.
- Further research can unlock broader applications in food processing and biomedicine.
Keywords:
CelluloseCellulose compositesEnzyme immobilizationEnzyme performanceFunctionalized celluloseMore Related Videos
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