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Updated: Feb 1, 2026
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Generation of Lymph Node-fat Pad Chimeras for the Study of Lymph Node Stromal Cell Origin
Published on: December 16, 2013
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Diagnostic Dilemma in a Lymph Node Aspiration Cytology
Nitika Gupta1, Nilay Nishith1, Sankalp Sancheti1
1Department of Pathology, Homi Bhabha Cancer Hospital and Research Centre, Tata Memorial Centre, Homi Bhabha National Institute (HBNI), Punjab, India.
Summary
A rare supraclavicular lymph node mass in a 35-year-old woman was diagnosed using fine needle aspiration. Cytology revealed spindle cells and osteoclast-like giant cells, prompting further discussion.
Area of Science:
- Oncology
- Pathology
- Cytology
Background:
- Enlarged supraclavicular lymph nodes can indicate various pathologies.
- Fine needle aspiration (FNA) is a key diagnostic tool for lymph node evaluation.
Purpose of the Study:
- To present a case of an unusual lymph node finding.
- To highlight the cytological features of a rare condition.
Main Methods:
- Fine needle aspiration (FNA) cytology of a right supraclavicular lymph node.
- Morphological analysis of cytological smears.
Main Results:
- A 2-cm enlarged right supraclavicular lymph node was identified.
- Cytological examination revealed abundant spindle cells.
- Numerous osteoclast-like giant cells were observed in the smears.
Conclusions:
- The cytological findings suggest a rare differential diagnosis for supraclavicular lymphadenopathy.
- Further investigation and discussion are warranted for definitive diagnosis.
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