Related Experiment Video
Updated: Feb 3, 2026

A High-Throughput Method For Zebrafish Sperm Cryopreservation and In Vitro Fertilization
Published on: July 6, 2009
In Vitro Fertilization Utilization Rates and Outcomes in States With and Without Insurance Coverage Mandates for Male
Amelia A Khoei1, Phyllis Yan1, Rodney L Dunn1
1Department of Urology, University of Michigan, Ann Arbor, MI.
Objective:
To compare IVF utilization rates and IVF outcomes in states with and without mandates for male infertility coverage. In 2020, 43 states recorded their lowest fertility rate in 3 decades. In-vitro fertilization (IVF) is an important treatment for couples affected by infertility, including 50% of couples with male factor infertility as a contributing cause. As of 2020, 12 states had passed laws mandating insurance coverage for IVF; only 7 of those states also mandated coverage for male infertility care.
Methods:
We obtained nationwide claims data from over 91 million insured US individuals from 2003 to 2020 in Optum's de-identified Clinformatics Data Mart Database. States were categorized into 3 groups: states mandating IVF and male infertility care coverage, states mandating only IVF coverage, and all remaining states. We calculated IVF utilization rates and pregnancy, live, multiple, and preterm birth rates following IVF.
Results:
IVF utilization was 6-fold higher in states with mandated male infertility coverage compared to states without any mandated coverage. Pregnancy and birth rates after IVF were similar across groups. The absolute number of births from IVF per 100,000 women was highest in states with insurance coverage mandates that included male infertility care.
Conclusion:
IVF utilization rates and absolute number of live births from IVF were highest in states with an insurance mandate that included male infertility care. In the setting of declining fertility rates, policymakers drafting new legislation for infertility coverage should consider including coverage for male infertility care to promote family-building.
Related Concept Videos
Infertility in Males
In Vitro Fertilization
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
Infertility in Females
Endometriosis, a condition characterized by abnormal growth of...
Fertilization
Predicting Reaction Outcomes
Measuring Reaction Rates

