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Updated: Feb 3, 2026

The Terroir Concept Interpreted through Grape Berry Metabolomics and Transcriptomics
Published on: October 5, 2016
Transcriptomic analysis identifies VvMYB90 and VvNAC92 as key regulators mediating anthocyanin biosynthesis and fruit
Han Lin1, Kaili Mao1, Shilong Chai1
1College of Horticulture / Institute of Storage, Transportation and Preservation of Horticultural Products, Fujian Agriculture and Forestry University, Fuzhou, Fujian 350002, China.
Abstract:
'Shine Muscat' (YG), 'Gaoqiansui' (GQS), and 'Moldova' (ME) are three grape cultivars with distinct phenotypic differences in fruits, serving as ideal materials for deciphering the mechanism of grape color differentiation. Currently, the specific mechanisms underlying the regulation of anthocyanin synthesis and color differentiation during grape fruit development require further investigation. To understand these, transcriptomic analysis was performed in this study to compare the different developmental stages of the three grape cultivars. Transcriptomic analysis displayed significant enrichment of differentially expressed genes (DEGs) in the phenylpropanoid and flavonoid biosynthesis pathways. These pathway-related genes exhibited a significant upregulation in expression during the veraison and maturation stages in the GQS and ME groups, with the most prominent upregulation observed in the ME group. Meanwhile, WGCNA and correlation network heatmap were employed to construct a TF-structural gene regulatory network associated with grape anthocyanin synthesis. VvMYB90 may mediate the regulation of gene-UFGT, whereas VvNAC92 may engage in the regulation of seven structural genes (gene-CHS, gene-GST4, gene-LOC100250360, gene-LOC100250579, gene-LOC100255217, gene-LOC100261962, and gene-UFGT). Collectively, these findings reveal the molecular basis of anthocyanin biosynthesis and color differentiation in grape fruits, providing meaningful insights into the accurate regulation of grape peel color.
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