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Optimization of the Retinal Vein Occlusion Mouse Model to Limit Variability
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RVO-ME: A Dual-Task OCT Dataset for Segmentation and Detection of Macular Lesions in Retinal Vein Occlusion
Fen Xiong1, Guodong Li1, Weihao Gao2
1Ophthalmic Center, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, 330000, P.R. China.
Scientific Data
|February 4, 2026
Summary
A new dataset of 3,012 OCT B-scans aids artificial intelligence development for retinal vein occlusion (RVO) with macular edema (ME). This resource supports automated analysis of RVO-ME, improving diagnostic accuracy and patient outcomes.
Area of Science:
- Ophthalmology
- Medical Imaging
- Artificial Intelligence
Background:
- Retinal vein occlusion (RVO) is a leading cause of vision loss, often complicated by macular edema (ME).
- Optical coherence tomography (OCT) is crucial for diagnosing and monitoring RVO-ME.
- Automated RVO-ME analysis is limited by a lack of high-quality annotated datasets.
Purpose of the Study:
- To create a manually annotated dataset of OCT B-scans for RVO-ME analysis.
- To provide a benchmark for evaluating automated segmentation algorithms.
- To advance artificial intelligence (AI) models for RVO-related diseases.
Main Methods:
- Compiled 3,012 OCT B-scans from 146 eyes (130 patients) with RVO-ME.
- Provided segmentation labels for subretinal fluid, intraretinal fluid, ellipsoid zone, and external limiting membrane.
- Included point annotations for detecting highly reflective foci.
Main Results:
- Developed a comprehensive RVO-ME OCT dataset.
- The dataset includes detailed annotations for key retinal structures and fluid indicators.
- Facilitates quantitative analysis and algorithm development.
Conclusions:
- The new dataset addresses the critical need for annotated data in RVO-ME research.
- It serves as a valuable resource for developing and validating AI-driven diagnostic tools.
- Expected to accelerate progress in automated analysis of RVO-ME using OCT imaging.
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