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Updated: Feb 9, 2026

Rapid and Specific Detection of Acinetobacter baumannii Infections Using a Recombinase Polymerase Amplification/Cas12a-based System
Published on: April 25, 2025
Structure and gene cluster of the capsular polysaccharide of Acinetobacter baumannii K223
Andrei V Filatov1, Anna M Shpirt1, Andrei V Perepelov1
1N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Abstract:
Structure of the Acinetobacter baumannii strain MAR22-475 classified to KL223 type capsular polysaccharide (CPS) was established by component analyses, Smith degradation as well as 1H and 13C NMR spectroscopy, including two-dimensional homonuclear 1Н,1Н COSY, TOCSY, ROESY and heteronuclear 1Н,13C HSQC and HMBC experiments. The K223 CPS is composed of branched tetrasaccharide K-units containing two d-Glсp residues, and one residue each of d-GlcpNAc and d-Galp. The following structure of the tetrasaccharide repeating unit of the CPS was established.
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