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Selected Genes Associated With CVD-Related Diseases, Pathways, and Nutrigenetics
Seyma Sehadet Tasdemir1,2, Gamze Akbulut3
1Department of Nutrition and Dietetics, Bitlis Eren University, Bitlis, Turkey.
Journal of Lipid and Atherosclerosis
|February 9, 2026
Summary
Personalized nutrition, guided by genetic insights, offers a novel approach to combat cardiovascular disease (CVD). Understanding gene-diet interactions can optimize dietary strategies for better cardiovascular health outcomes.
Area of Science:
- Cardiovascular Science
- Nutrigenetics
- Nutrigenomics
Background:
- Cardiovascular disease (CVD) is a major health concern, often driven by atherosclerosis and influenced by nutrition.
- While nutrition is a key modifiable factor, its impact on CVD mortality is limited by genetic variability.
- Interindividual differences in genetic makeup affect how people respond to dietary interventions.
Purpose of the Study:
- To explore the role of genetic factors in cardiovascular health and disease.
- To review the science of nutrigenetics and nutrigenomics in the context of CVD.
- To highlight the potential of personalized nutrition for CVD prevention and management.
Main Methods:
- Review of scientific literature on CVD, nutrition, and genetics.
- Analysis of nutrient-gene interactions and their impact on cardiovascular health.
- Discussion of personalized nutrition strategies based on genetic profiles.
Main Results:
- Genetic variations significantly influence individual responses to dietary components.
- Nutrigenetics and nutrigenomics provide a framework for understanding these gene-diet interactions.
- Personalized nutrition, tailored to genetic profiles, shows promise for enhancing CVD prevention.
Conclusions:
- Aligning dietary treatments with individual genetic profiles is crucial for effective CVD management.
- Personalized nutrition strategies can potentially improve life expectancy and promote sustainable healthy living.
- Further research into gene-diet interactions is essential for advancing CVD prevention through tailored nutrition.
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