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Updated: Feb 14, 2026

Glycopeptide Capture for Cell Surface Proteomics
Published on: May 9, 2014
Chemoenzymatic synthesis of sulfated O-glycopeptides from human CD34
Yinyu Jiang1,2, Qi Du3, Fengzhuo Wu2
1State Key Laboratory of Chemical Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China. mwj@xjtu.edu.cn.
Abstract:
O-Glycosylation is a key modulator of CD34 biofunction. To investigate the distinct roles of different glycoform modifications, we report an efficient chemoenzymatic strategy to rapidly assemble a library of CD34 O-glycopeptides bearing sulfated and sialylated glycan variants, enabling the elucidation of how specific glycan modifications govern molecular recognition events.
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