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A Protocol to Set Up Needle-Free Connector with Positive Displacement on Central Venous Catheter in Intensive Care Unit
Published on: July 13, 2019
ANTIBIOGRAM OF URINARY CATHETER-ASSOCIATED BACTERIAL PATHOGENS IN INTENSIVE CARE UNIT, KING KHALID GENERAL HOSPITAL,
11Hafar Al-Batin Health Cluster- Saudi Arabia.
Background:
Patients in intensive care units are more susceptible to catheter-associated urinary tract infections (CAUTIs) caused by drug resistant bacteria.
Methods:
This retrospective study was done to determine the antibiogram of Urinary Catheter-associated Bacterial Pathogens in the Intensive Care Unit, at King Khalid General Hospital, Saudi Arabia, using full automated MicroScan walkaway 96 plus Beckman Coulter.
Results:
Among the identified bacteria, Escherichia coli and Klebsiella pneumoniae were the most prevalent, accounting for 33.7% (29/86) and 23.3% (20/86), respectively. High resistance was documented against ciprofloxacin 75.6% (65/86), cefuroxime 69.8% (60/86), levofloxacin 68.6% (59/86) and amoxicillin/clavulinic acid 65.1% (56/86), but Colistin showed high activity against the isolated bacteria with low resistance rate 5.81 % (5/86). Frequency of multi-drug-resistant bacteria revealed a rate of 65.1% (56/86). Resistance to piperacillin/tazobactam and cefuroxime was significantly associated with length of stay in the intensive care unit, duration of antimicrobial use, and catheterization duration with a p<0.05. Also, the results strongly indicated that resistance to all cephalosporins examined was significantly associated with long stay in ICU.
Conclusion:
The identified bacteria among CAUTIs displayed resistance to at least one agent in three or more antimicrobial groups, indicating high resistance of common prescribed antibacterial agent in the study area.
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