Comparison of a new non-contact automatic ophthalmic optical biometer with an SS-OCT based optical biometer ARGOS

To evaluate the agreement of ocular biometric parameters measured by a novel all-in-one optical low coherence reflectometry (OLCR) biometer (SW-9000 Plus) compared with a swept-source optical coherence tomography (SS-OCT) biometer (ARGOS).

48 eyes of 48 healthy subjects were included. The following parameters were obtained: axial length (AL), central corneal thickness (CCT), anterior chamber depth (ACD), lens thickness (LT), mean keratometry (Km), astigmatism (AST), J₀, J₄₅, corneal diameter (CD) and pupil diameter (PD). Bland-Altman plots and 95% limits of agreement (LoA) were utilized to confirm the concordance between the devices. Participants were categorized into two groups based on AL to facilitate a subgroup analysis (AL > 25 mm or AL < 25 mm).

The new biometer showed small differences with SS-OCT: AL (0.01 ± 0.03 mm), CCT (4.65 ± 4.29 μm), ACD (-0.11 ± 0.05 mm), LT (0.03 ± 0.08 mm), Km (-0.08 ± 0.18 D), AST (-0.03 ± 0.17 D), J₀ (0 ± 0.09 D), J₄₅ (-0.05 ± 0.09 D), CD (-1.21 ± 0.36 mm), and PD (-0.37 ± 0.64 mm). For AL > 25 mm and AL < 25 mm, differences were 0.02 ± 0.03 mm and -0.01 ± 0.03 mm. Bland-Altman plots showed narrow 95% LoAs for all except PD (-1.62 to 0.87 mm) and CD (-1.91 to -0.51 mm).

The novel all-in-one OLCR biometer showed high agreement with the SS-OCT device for most ocular biometry parameters in healthy eyes. CD and PD demonstrated lower agreement and should not be considered interchangeable between devices.