Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Mechanism of Angiogenesis01:10

Mechanism of Angiogenesis

6.4K
Blood vessel formation starts early during embryonic development, around day 7. In the extraembryonic yolk sac, mesodermal precursor cells called hemangioblast proliferate and differentiate into angioblast. Angioblasts express vascular endothelial growth factor receptor 2 or VEGFR2, which binds VEGF-A, a proangiogenic factor, guiding blood vessel formation. VEGF signaling promotes angioblasts to form a blood island in the developing embryo. Angioblasts further differentiate, giving rise to...
6.4K
Regulation of Angiogenesis and Blood Supply01:24

Regulation of Angiogenesis and Blood Supply

2.9K
Rapidly dividing tumors, embryos, and wounded tissues require more oxygen than usual, lowering the oxygen concentration in the blood. At low oxygen or hypoxic conditions, an oxygen-sensitive transcription factor called the hypoxia-inducible factor 1 or HIF1 is activated. HIF1 is a dimeric protein of alpha (ɑ) and beta (β) subunits.  Under optimal oxygen conditions, HIF1β is present in the nucleus while HIF1ɑ remains in the cytosol. HIF1ɑ is hydroxylated by prolyl...
2.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hydrogen-bond-regulated optical band-gap engineering and transparency in semi-organic L-glycine succinate crystals.

Journal of molecular modeling·2026
Same author

Lymph Node Simulator of the Neck Region: A Novel Teaching-Learning Tool.

Journal of dental education·2026
Same author

Fluid Resuscitation in Oral & Maxillofacial Trauma.

Journal of maxillofacial and oral surgery·2026
Same author

In silico Docking Study of Allicin Targeting Streptococcus mutans for the Treatment of Dental Caries.

Annals of African medicine·2025
Same author

Antibacterial Assessment of Allium sativum against Oral Pathogens - An in vitro Study.

Annals of African medicine·2025
Same author

Gender Difference in Pain Perception and Post-surgery Satisfaction Following Impacted Mandibular Third Molar Surgery - A Comparative Study.

Annals of maxillofacial surgery·2025

Related Experiment Video

Updated: May 6, 2026

Isolation of Murine Embryonic Hemogenic Endothelial Cells
08:56

Isolation of Murine Embryonic Hemogenic Endothelial Cells

Published on: June 17, 2016

12.2K

Hemangioendothelioma - A Case Report.

Preethi Murali1, B Kavitha2, Pradeep Devadoss3

  • 1Department of Research, Meenakshi Ammal Dental College and Hospital, MAHER, Chennai, Tamil Nadu, India.

Indian Journal of Dental Research : Official Publication of Indian Society for Dental Research
|February 16, 2026
PubMed
Summary

This case study details a rare borderline vascular neoplasm, haemangioendothelioma, found in a 67-year-old male's jaw. Diagnosis involved clinical, radiological, and histopathological analysis, highlighting this tumor

More Related Videos

A Patient-Derived Xenograft Model for Venous Malformation
06:51

A Patient-Derived Xenograft Model for Venous Malformation

Published on: June 15, 2020

5.8K
Surgical Treatment of an Endolymphatic Sac Tumor
04:34

Surgical Treatment of an Endolymphatic Sac Tumor

Published on: May 26, 2023

1.6K

Related Experiment Videos

Last Updated: May 6, 2026

Isolation of Murine Embryonic Hemogenic Endothelial Cells
08:56

Isolation of Murine Embryonic Hemogenic Endothelial Cells

Published on: June 17, 2016

12.2K
A Patient-Derived Xenograft Model for Venous Malformation
06:51

A Patient-Derived Xenograft Model for Venous Malformation

Published on: June 15, 2020

5.8K
Surgical Treatment of an Endolymphatic Sac Tumor
04:34

Surgical Treatment of an Endolymphatic Sac Tumor

Published on: May 26, 2023

1.6K

Area of Science:

  • Vascular Oncology
  • Surgical Pathology
  • Head and Neck Neoplasms

Background:

  • Vascular neoplasms encompass benign, malignant, and reactive tumors.
  • Haemangioendothelioma represents an intermediate-grade, borderline vascular neoplasm.

Purpose of the Study:

  • To present a case of haemangioendothelioma in the left lower jaw.
  • To discuss the diagnostic approach and characteristics of vascular neoplasms, focusing on haemangioendothelioma.

Main Methods:

  • Clinical examination of a patient with a jaw swelling.
  • Radiological imaging to assess the lesion.
  • Histopathological analysis for definitive diagnosis.

Main Results:

  • A 67-year-old male presented with a year-long left lower jaw swelling.
  • Diagnosis of haemangioendothelioma was confirmed through integrated clinical, radiological, and histopathological findings.

Conclusions:

  • Haemangioendothelioma is a rare borderline vascular neoplasm.
  • Comprehensive diagnostic methods are crucial for identifying such tumors.
  • This case underscores the importance of detailed evaluation for vascular neoplasms in the head and neck region.