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[Healthcare Research in Renal Cell Cancer: 7-Year-Data from the VERSUS Study by d-uo]
Manfred Johannsen1,2, Rolf Eichenauer2,3, Jörg Klier2,4
1Facharztpraxis Urologie, Urologie, Germany, Berlin.
Aktuelle Urologie
|February 16, 2026
Summary
This study analyzed 2,526 renal cell carcinoma (RCC) patients in Germany, revealing differences in diagnosis and treatment between genders. Further research requires comprehensive national cancer registries for improved quality assurance.
Area of Science:
- Urology
- Oncology
- Healthcare Research
Background:
- Renal cell carcinoma (RCC) represents 13.5% of urological tumors.
- Healthcare research evaluates the implementation of clinical trial treatments and guidelines in routine care.
- The prospective VERSUS study (VERSorgUngsStudie) by d-uo (
- Deutsche Uro-Onkologen
- ) provides data on RCC diagnosis, treatment, and aftercare.
Purpose of the Study:
- To present healthcare research data on RCC based on results from the prospective VERSUS study.
- To analyze diagnosis, treatment, and aftercare patterns in uro-oncological patients.
- To identify potential improvements for quality assurance in oncological care.
Main Methods:
- Prospective, non-interventional, multicentric study design.
- Inclusion of 31,419 uro-oncological patients, with 2,526 diagnosed with RCC.
- Descriptive analysis of diagnosis, tumor stage, treatment, and aftercare data.
Main Results:
- Diagnosis was symptom-driven in 22.7% and screening-detected in 38.1% of RCC cases.
- Symptomatic men presented with advanced stages (UICC III/IV) more frequently (38.3%) than women (24.8%).
- Nephrectomy rate in stage T1 was 25.9%; systemic therapy was given to 13.1% of evaluable cases.
Conclusions:
- The VERSUS study provides current data on RCC but is limited by data depth, similar to the German cancer registry.
- Development of organ-specific cancer registries, like the planned Renal Cancer National Registry (ReNAT), is crucial.
- National registries will enhance healthcare research and quality assurance for oncological care in Germany.
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