[Medical Devices for Evaluating Cerebral Blood Flow and its Evaluation Method].

Area of Science:

• Neurology
• Radiology
• Medical Imaging

Background:

• Neuroimaging is crucial for acute ischemic stroke treatment decisions.
• Understanding the mismatch between ischemic core and penumbra guides therapy.
• Recanalization therapy aims to restore blood flow and salvage penumbra.

Purpose of the Study:

• To evaluate the role of neuroimaging in acute ischemic stroke triage.
• To assess perfusion imaging for differentiating ischemic core and penumbra.
• To highlight the utility of automated software in stroke imaging analysis.

Main Methods:

• Review of neuroimaging techniques in acute ischemic stroke.
• Analysis of perfusion imaging (CT perfusion) for core and penumbra assessment.
• Discussion of automated postprocessing software for volumetric calculations.

Main Results:

• Perfusion imaging noninvasively evaluates ischemic core and penumbra.
• Automated software rapidly calculates core and penumbra volumes.
• CT perfusion may have variability in core volume estimation.

Conclusions:

• Neuroimaging is essential for guiding endovascular treatment in acute ischemic stroke.
• Accurate assessment of ischemic core and penumbra is key to successful recanalization therapy.
• Discordant findings may suggest stroke mimics, requiring further investigation.