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Related Experiment Video

Updated: May 5, 2026

Automated Counterflow Centrifugal System for Small-Scale Cell Processing

Automated Counterflow Centrifugal System for Small-Scale Cell Processing

Published on: December 12, 2019

Foehn: An open-hardware asynchronous scheduling hub for high-throughput liquid-handling workflow.

Yueyang Gao¹, Jacob Danks¹, Simon Dawes²

¹Department of Chemical Engineering, University College London, London WC1E 7JE, UK.

|February 18, 2026

Summary

This summary is machine-generated.

A new system called Foehn enables laboratory robots to perform multiple tasks simultaneously, overcoming limitations in high-throughput experimentation. This asynchronous scheduling hub enhances scalability and efficiency in automated research workflows.

Keywords:

Asynchronous operation High-throughput experimentation Lab automation Liquid handling robots

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Area of Science:

Automation and Robotics
Laboratory Science
Biotechnology

Background:

High-throughput experimentation demands advanced laboratory automation.
Liquid-handling robots are crucial but limited by sequential operations, hindering scalability.
Existing systems lack efficient concurrent control for multiple experimental modules.

Purpose of the Study:

To develop an asynchronous scheduling hub system, Foehn, for concurrent control of laboratory automation modules.
To address the scalability bottleneck in liquid-handling robot workflows.
To create a flexible, cost-effective, and open-source control architecture.

Main Methods:

Developed Foehn using open-source Arduino hardware and a Python GUI.
Implemented asynchronous, multi-threaded operation via standardized serial protocols.
Integrated liquid-handling robots with peripheral modules (pumps, stirrers).

Main Results:

Foehn demonstrated stable voltage output and 87.6% pulse-width modulation control efficiency.
Successfully executed concurrent pumping and stirring with simultaneous pipetting and labware movement.
Showcased excellent synchronization and operational stability across hardware layers.

Conclusions:

The Foehn system offers a scalable foundation for high-throughput automation.
Its modular, open-source design enhances flexibility and reduces costs.
Foehn has strong potential to accelerate research in chemistry, biology, and materials science.