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Polymicrobial Emphysematous Hepatitis With Clindamycin-Resistant Clostridium Perfringens in a Patient With Pancreatic
Newton Nguyen Khoa Bui Le1,2, Nicholas Fanous1,2, James Pham1,3
1St Vincent's Hospital, Sydney, New South Wales, Australia.
ACG Case Reports Journal
|February 19, 2026
Summary
Emphysematous hepatitis (EH), a severe liver infection, presents with gas in liver tissue. This case highlights a rare Clostridium perfringens strain resistant to clindamycin, impacting treatment strategies.
Area of Science:
- Hepatology
- Infectious Diseases
- Oncology
Background:
- Emphysematous hepatitis (EH) is a rare, life-threatening liver infection characterized by gas within the liver parenchyma.
- It has a high mortality rate, exceeding 70%, and is often associated with biliary obstruction or malignancy.
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