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Alternative RNA Splicing

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Alternative RNA splicing is the regulated splicing of exons and introns to produce different mature mRNAs from a single pre-mRNA. Unlike in constitutive splicing where a single gene produces a single type of mRNA, alternative splicing allows an organism to produce multiple proteins from a single gene and plays an important role in protein diversity.
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Updated: Feb 21, 2026

Author Spotlight: Innovative Approaches to Understanding Plant Structure-Function Relationships for Climate-Resilient Crops

Author Spotlight: Innovative Approaches to Understanding Plant Structure-Function Relationships for Climate-Resilient Crops

Published on: July 12, 2024

Alternative splicing and climate-resilient crops.

Yingying Tan¹, Siying Ye¹, Anqi Zhang¹

¹Integrative Science Center of Germplasm Creation in Western China (Chongqing) Science City, College of Agronomy and Biotechnology, Southwest University, Chongqing 400715, China.

Trends in Genetics : TIG

|February 19, 2026

Summary

This summary is machine-generated.

Abiotic stresses impact plant growth, but alternative splicing (AS) offers molecular plasticity for adaptation. Understanding AS regulation is key to breeding climate-resilient crops.

Keywords:

abiotic stress alternative splicing molecular breeding sQTL splicing factor transcriptome

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Area of Science:

Plant biology
Molecular genetics
Genomics

Background:

Abiotic stresses like drought and salinity limit plant growth and crop yield, threatening food security.
Alternative splicing (AS) is a crucial gene regulatory mechanism that enhances molecular plasticity for rapid environmental adaptation in plants.

Purpose of the Study:

To synthesize current knowledge on plant alternative splicing mechanisms and detection.
To review stress-induced AS regulation under various abiotic conditions.
To discuss the potential of AS manipulation for breeding climate-resilient crops.

Main Methods:

Genome-wide profiling using high-throughput sequencing technologies.
Literature synthesis on AS mechanisms, detection, and stress responses.
Analysis of AS impacts on genes involved in stress signaling and regulation.

Main Results:

Abiotic stresses significantly alter plant splicing landscapes.
AS affects transcripts encoding key stress-response proteins, including transcription factors and signaling components.
Splicing regulators themselves are subject to AS, creating complex regulatory networks.

Conclusions:

Alternative splicing is a vital mechanism for plant adaptation to abiotic stress.
Targeting AS presents a promising strategy for developing crops with enhanced stress resistance.
This approach offers a paradigm for genetic improvement beyond stress tolerance.