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Published on: March 15, 2012
New Alkaloid From the Marine-Derived Fungus Aspergillus sp. MF01
Xiu-Rong Zhou1, Yan-Wen Wu1, Jun-Yi Wu1
1School of Food and Pharmacy, Zhejiang Ocean University, Zhoushan, China.
Abstract:
Two compounds, including one new alkaloid, namely, aspergilloid A (1), together with one known compound (2), were isolated from the sponge-derived fungus Aspergillus sp. MF01. The structure of one undescribed compound was elucidated by NMR, HRESIMS, and electronic circular dichroism (ECD) diffraction spectroscopy. All the isolated compounds were evaluated for their antimicrobial activities. Compound 1 showed weak antibacterial activity against Gram-positive bacteria Staphylococcus aureus and Staphylococcus epidermidis at 1 mg/mL.
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