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Author Spotlight: Quantifying Pain Experience – An Illustrative Approach Using the Pain Body Diagram

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Published on: July 7, 2023

A Self-Reported Electronic Body Map Identifies Distinct Clinical Pain Phenotypes in Chronic Pancreatitis.

Jorge D Machicado¹, David Guevara-Lazo¹, Jonathan P Troost²

¹Division of Gastroenterology and Hepatology, University of Michigan, Ann Arbor, Michigan, USA.

Clinical and Translational Gastroenterology

|February 20, 2026

Summary

Widespread pain, identified using a simple body map in chronic pancreatitis (CP) patients, is linked to more severe symptoms and nociplastic pain features. This tool may help tailor pain management strategies for CP.

Keywords:

central nervous system centralized pain chronic pain pain mechanism pancreatitis

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Area of Science:

Gastroenterology
Pain Medicine
Neurology

Background:

Chronic pancreatitis (CP) can cause nociplastic pain due to central nervous system dysregulation.
Diagnosing nociplastic pain in CP is challenging due to a lack of bedside tools.
Body maps assess pain widespreadness in chronic pain, but their use in CP is not well-established.

Purpose of the Study:

To investigate the association between pain widespreadness, measured by a body map, and nociplastic pain features in patients with CP.

Main Methods:

A cross-sectional analysis of 110 adults with definite CP was conducted.
Pain widespreadness was assessed using the Michigan Body Map, categorizing pain as localized or widespread (≥3 regions).
Validated surveys measured clinical features of nociplastic pain, with multivariable regression analyses performed.

Main Results:

64% of CP patients with abdominal pain reported widespread pain.
Widespread pain correlated with increased pain severity, pain interference, and neuropathic pain scores.
Widespread pain was also associated with greater fatigue, impaired physical functioning, chronic overlapping pain conditions, and poorer health outcomes.

Conclusions:

A significant proportion of CP patients exhibit widespread pain, identifiable via a body map.
This subgroup presents with more severe symptoms and indicators of nociplastic pain.
A body map may serve as a practical tool for identifying patients who could benefit from targeted, mechanism-based pain management in CP.