Alternating current polarity for electrochemical de novo synthesis of 3,3'-bisoxindoles
Jian Wang1, Shenglin Chen2, Daokuan Sun1
1Institute of Drug Discovery Technology, Ningbo University, Zhejiang, China. wuju@nbu.edu.cn.
Abstract:
A radical-involved cascade reaction provides straightforward and efficient access to structurally complex building blocks from readily available substrates. Herein, we report an unprecedented electrochemical synthesis of 3,3'-bisoxindoles through three newly formed C-C bonds enabled by alternating current polarity, which obviates the need for external oxidants and showcases excellent chemoselectivity.
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