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Harmonizing Medicare Claims Data with OMOP: A Validated ETL Pipeline
Yao An Lee1, Ying Lu1, Jiang Bian2,3
1Department of Pharmaceutical Outcomes & Policy, College of Pharmacy, University of Florida, Gainesville, Florida, USA.
AMIA ... Annual Symposium Proceedings. AMIA Symposium
|February 23, 2026
Summary
This study developed a Python ETL pipeline to convert Medicare claims into the OMOP Common Data Model, ensuring high data quality and enabling large-scale health research.
Area of Science:
- Health Informatics
- Data Science
- Biomedical Research
Background:
- Medicare Limited Data Set (LDS) claims are valuable for research but lack standardization.
- The Observational Medical Outcomes Partnership (OMOP) Common Data Model (CDM) provides a standardized format for observational health data.
- Integrating Medicare LDS data into the OMOP CDM is crucial for large-scale health services research.
Purpose of the Study:
- To develop and validate a Python-based Extract, Transform, Load (ETL) pipeline for converting Medicare LDS claims to the OMOP CDM.
- To assess the data fidelity and completeness of the conversion process.
- To facilitate standardized healthcare data utilization for observational research.
Main Methods:
- Developed a Python ETL pipeline to map Medicare LDS tables to fifteen OMOP CDM tables.
- Utilized the OMOP Data Quality Dashboard for rigorous validation of the transformed data.
- Conducted comparative analyses to evaluate concordance between original and transformed datasets.
Main Results:
- Achieved minimal data loss during the mapping of Medicare LDS tables to OMOP CDM.
- OMOP Data Quality Dashboard validation showed a 99% pass rate across over 1,500 checks.
- Demonstrated high concordance in demographic traits and clinical conditions between datasets, despite minor unmapped codes.
Conclusions:
- The developed ETL pipeline effectively standardizes Medicare LDS data into the OMOP CDM with high fidelity.
- This scalable and reproducible approach addresses critical data integration gaps for health services research, population health, and policy analysis.
- Future work will focus on incorporating additional clinical details and advanced concept mappings for enhanced data utility.
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