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Related Concept Videos

Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

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The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
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Related Experiment Video

Updated: Feb 26, 2026

Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries
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Association between Live Dietary Microbes and Root Caries: A Cross-Sectional Study with a Predictive Risk Model.

Donglei Wu, Zhengshen Lin, Peng Zhou

    Oral Health & Preventive Dentistry
    |February 24, 2026
    PubMed
    Summary
    This summary is machine-generated.

    Higher intake of live dietary microbes is linked to reduced root caries. This study developed a predictive model to identify individuals at high risk for root caries, aiding preventive strategies.

    Keywords:
    cross-sectional studydietary habitsepidemiologylive dietary microbesoral biofilmsroot caries

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    Area of Science:

    • Oral Health Research
    • Microbiome Studies
    • Preventive Dentistry

    Background:

    • Root caries is a significant oral health concern, particularly in aging populations.
    • Dietary factors play a crucial role in oral health, but the impact of live dietary microbes is underexplored.

    Purpose of the Study:

    • To examine the association between medium-to-high (MedHi) levels of live dietary microbe intake and root caries prevalence.
    • To create a predictive model for estimating root caries risk.

    Main Methods:

    • Cross-sectional analysis of National Health and Nutrition Examination Survey (NHANES) data (2015-2020).
    • Dietary intake assessed via 24-h recalls; root caries determined by oral examinations.
    • Logistic regression and LASSO regression used to identify risk factors and build a predictive model.

    Main Results:

    • MedHi live dietary microbe intake, age, education, smoking, flossing, and systemic conditions were associated with root caries (P<0.05).
    • The developed predictive model showed good discrimination and calibration in both training and testing datasets.

    Conclusions:

    • Increased intake of live dietary microbes correlates with a lower prevalence of root caries.
    • The predictive model can assist clinicians in identifying high-risk individuals for targeted preventive interventions.
    • Further research is needed to establish causality between dietary microbes and oral health outcomes.