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Related Concept Videos

The Oral Microbiota01:27

The Oral Microbiota

The oral microbiome includes a complex ecosystem comprising over 700 microbial species, identified through genomic sequencing and culture-based analyses to date. This community includes a core microbiome, found universally among individuals, and a variable component influenced by environmental factors such as diet, lifestyle, and host genetics. Site-specific conditions, including oxygen gradients, pH levels, and nutrient availability, determine the spatial distribution of these microorganisms...
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Related Experiment Video

Updated: Jun 26, 2026

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
07:15

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils

Published on: January 21, 2020

Association Between Ankylosing Spondylitis and Periodontitis: A Systematic Review.

Valentin Quemard, Zocko Ange Désiré Pockpa, Christian Verner

    Oral Health & Preventive Dentistry
    |June 25, 2026
    PubMed
    Summary
    This summary is machine-generated.

    This review explored the link between ankylosing spondylitis (AS) and periodontitis (PD). While prevalence is unclear, periodontal disease correlates with AS and may impact treatment, suggesting potential benefits from screening and managing PD in AS patients.

    Keywords:
    ankylosing spondylitisperiodontal diseasesperiodontitisspondyloarthritissystematic review

    Related Experiment Videos

    Last Updated: Jun 26, 2026

    Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
    07:15

    Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils

    Published on: January 21, 2020

    Area of Science:

    • Rheumatology
    • Periodontology
    • Immunology

    Background:

    • Ankylosing spondylitis (AS) and periodontitis (PD) are chronic inflammatory conditions.
    • Understanding potential associations between AS and PD is crucial for patient management.

    Purpose of the Study:

    • To systematically review the existing literature on the association between ankylosing spondylitis and periodontitis.
    • To evaluate the prevalence and clinical parameters of periodontitis in AS patients.

    Main Methods:

    • Systematic literature search conducted in PubMed, Cochrane Library, Scopus, and Web of Science following PRISMA 2020 guidelines.
    • Included 18 eligible studies (cohort, case-control, Mendelian randomization) assessed for quality using SIGN and STROBE-MR.
    • Keywords focused on spondyloarthritis, ankylosing spondylitis, periodontal diseases, and periodontitis.

    Main Results:

    • Prevalence of PD in AS patients yielded conflicting results.
    • Periodontal parameters (BOP, PPD, CAL) showed correlations with AS parameters, though not always statistically significant.
    • PD significantly increased inflammatory markers (IL-6, TNF-α, CRP, ESR) in AS patients; anti-TNF-α therapy impacted periodontal parameters.

    Conclusions:

    • A definitive conclusion on increased PD prevalence in AS patients remains uncertain due to heterogeneous criteria.
    • Correlation between PD and AS parameters, and the effect of AS therapy on periodontal health, are significant findings.
    • Screening and treating PD in AS patients may offer clinical benefits, warranting further clinical trials.