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Updated: Feb 26, 2026

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Mimicking and Measuring Occlusal Erosive Tooth Wear with the "Rub&Roll" and Non-contact Profilometry
Published on: February 2, 2018
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Dentifrices for preventing erosive tooth wear: An in vitro comparative study
Juliellen Luiz da Cunha1, Anderson Gomes Forte2, Elizabeth Barreto Galvão de Souza1
1Graduate Program in Dentistry, Federal University of Paraíba (UFPB), João Pessoa, Brazil.
European Journal of Oral Sciences
|February 25, 2026
Summary
This study found that toothpastes combining fluoride with bioactive silica or stannous fluoride offer superior protection against erosive tooth wear. These formulations significantly enhance enamel resistance to acid and abrasion challenges.
Area of Science:
- Dental Science
- Materials Science
Background:
- Erosive tooth wear is a progressive demineralization of dental enamel.
- Preventive strategies are crucial for managing enamel compromise.
Purpose of the Study:
- To compare the protective effects of various fluoride-based dentifrices with bioactive agents against simulated erosive-abrasive challenges.
- To evaluate the impact of different bioactive ingredients on enamel resistance.
Main Methods:
- In vitro study using bovine enamel blocks subjected to 7-day pH cycling with acid challenges and brushing.
- Testing five dentifrice formulations: bioactive silica/sodium fluoride (BAS/NaF), stannous fluoride (SnF), sodium-calcium phosphosilicate/sodium fluoride (SCP/NaF), sodium fluoride (NaF), and fluoride-free (FF).
- Measurements included surface microhardness, roughness, fluorescence loss, and surface loss, analyzed with ANOVA.
Main Results:
- Bioactive silica/sodium fluoride (BAS/NaF) and stannous fluoride (SnF) dentifrices demonstrated superior protection, maintaining higher surface hardness and reducing surface and fluorescence loss.
- Sodium fluoride (NaF) and sodium-calcium phosphosilicate/sodium fluoride (SCP/NaF) showed intermediate protective effects.
- The fluoride-free (FF) control group exhibited the most significant mineral loss.
Conclusions:
- Fluoride-containing dentifrices with bioactive ingredients significantly enhance enamel resistance to erosive-abrasive challenges.
- Bioactive silica and stannous fluoride show the most promising effects in protecting enamel structure.
- These findings support the development of advanced dentifrices for managing erosive tooth wear.

