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Post-Intensive Care Syndrome in COVID-19 Patients in Spanish ICUs. One-Year Follow-Up. CoronaPICS Study
Ángela Alonso-Ovies1,2,3,4, María Ángeles de la Torre Ramos1,3, Carlos Velayos Amo1,2,3
1Servicio de Medicina Intensiva, Hospital Universitario de Fuenlabrada, Madrid, Spain.
Journal of Intensive Care Medicine
|February 25, 2026
Summary
This study followed COVID-19 survivors one year after intensive care, finding significant post-intensive care syndrome (PICS) symptoms. While many improved, physical, cognitive, and psychological deficits persisted, highlighting the need for ongoing support.
Area of Science:
- Critical Care Medicine
- Infectious Diseases
- Rehabilitation Medicine
Background:
- COVID-19 survivors often experience long-term health issues.
- Post-Intensive Care Syndrome (PICS) is a significant concern for critical illness survivors.
- Understanding PICS in COVID-19 patients is crucial for effective recovery.
Purpose of the Study:
- To characterize PICS in COVID-19 survivors from the first pandemic wave.
- To track PICS symptoms over a one-year follow-up period.
- To assess physical, cognitive, psychological, and nutritional recovery.
Main Methods:
- Prospective, observational, multicenter cohort study in 11 Spanish ICUs.
- Included critically ill adult COVID-19 survivors at risk for PICS.
- Follow-up at 3, 6, and 12 months post-discharge assessing various PICS domains.
Main Results:
- 40.9% experienced muscle weakness at 3 months, improving over time.
- High prevalence of anxiety (32.9%), depression (24.3%), PTSD (13.8%), and cognitive impairment (46.1%) at 3 months.
- Significant nutritional risk (42.4%) at 3 months, with gradual recovery; PTSD remained stable.
Conclusions:
- Critically ill COVID-19 patients exhibit significant PICS across multiple domains.
- Progressive improvement in PICS symptoms observed over one year.
- Physical, mental, cognitive, and nutritional support are vital for recovery.
Keywords:
COVID-19Critical care outcomesFollow-up clinicsPostintensive care syndromeQuality of lifeSARS CoV2critical illnessMore Related Videos
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