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Updated: Feb 28, 2026

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Identification of the Novel HLA-B*50:81N Allele Using PacBio Sequencing
Nan Xiao1, Wanzhen Yu2, Suning Bai2
1Dalian Blood Center, Liaoning, China.
HLA
|February 26, 2026
Summary
A novel HLA-B*50:81N allele was identified, differing from HLA-B*50:01:01:01 by a single nucleotide substitution. This finding contributes to the understanding of human leukocyte antigen diversity.
Area of Science:
- Immunogenetics
- Molecular biology
Background:
- The human leukocyte antigen (HLA) system is crucial for immune response.
- Polymorphisms within HLA genes contribute to immune diversity and disease susceptibility.
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