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Updated: Feb 27, 2026

In Silico Clinical Trials for Cardiovascular Disease
Published on: May 27, 2022
Artificial Intelligence and Digital Innovation in Cardiovascular Medicine
1University of Leicester, Leicester National Institute for Health and Care Research Biomedical Research Centre, Leicester, United Kingdom; British Heart Foundation Centre of Research Excellence, Leicester, United Kingdom; Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
Digital innovations like artificial intelligence are transforming cardiovascular medicine, especially in Asian populations. This review covers AI applications in prevention, diagnosis, and treatment, addressing implementation challenges for equitable precision cardiology.
Area of Science:
- Cardiovascular Medicine
- Digital Health
- Data Science
Background:
- Digital innovation and data science are revolutionizing cardiovascular medicine.
- Artificial intelligence (AI), machine learning (ML), and digital health tools are transitioning into clinical practice.
- Asian populations face a high burden of cardiovascular disease and unique healthcare challenges.
Purpose of the Study:
- To provide a comprehensive overview of digital innovations in cardiovascular medicine.
- To focus on applications and challenges within Asian populations.
- To outline the pathway toward equitable, scalable, and sustainable precision cardiology.
Main Methods:
- Review of developments across the cardiovascular care continuum.
- Highlighting large-scale cohort studies and risk prediction algorithms.
- Examining multimodal AI models, wearable devices, and assistive clinical tools.
Main Results:
- AI and digital tools are increasingly used in prevention, diagnosis, treatment, and follow-up.
- Large-scale studies and advanced algorithms are key drivers of progress.
- Wearable devices and assistive tools enhance patient care and clinical workflows.
Conclusions:
- Digital innovations offer significant potential for advancing precision cardiology.
- Addressing barriers like data quality, infrastructure, and regulations is crucial for implementation.
- Achieving equitable, scalable, and sustainable precision cardiology requires integrating research and clinical practice.
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