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First Report of Anchoring Via Trans-Leaflet Apposition Stent (ATLAS): Leaflet Modification for Failing Noncalcified
Danny Dvir1, Anna Turyan1, Amjad Abu Salman1
1Faculty of Medicine, Jesselson Integrated Heart Center, Shaare Zedek Medical Center, Hebrew University, Jerusalem, Israel.
JACC. Case Reports
|February 26, 2026
Summary
A novel technique anchors transcatheter valves in noncalcified aortic regurgitation (AR) by using a stent to secure the valve to the native leaflet. This ATLAS strategy offers a solution for patients lacking valve calcification.
Area of Science:
- Cardiovascular Surgery
- Interventional Cardiology
- Biomedical Engineering
Background:
- Aortic regurgitation (AR) often presents with noncalcified native valves, posing challenges for transcatheter valve anchoring.
- Current transcatheter valves rely on calcification for secure implantation, limiting options for many AR patients.

