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Aortic Regurgitation III: Medical Management

Aortic Regurgitation III: Medical Management

Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...

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Updated: Feb 28, 2026

Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement

Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement

Published on: March 26, 2018

Totally Endoscopic Approach for Aortic Valve Replacement: A Systematic Review and Single-Arm Meta-Analysis.

Florin Anghel^1,2,3, Mircea Ioan Alexandru Bistriceanu², Cristian Valentin Toma²

¹Department of Cardiovascular Surgery, Emergency University Hospital of Bucharest, 050098 Bucharest, Romania.

Medicina (Kaunas, Lithuania)

|February 27, 2026

Summary

This summary is machine-generated.

Totally endoscopic aortic valve replacement (TE-AVR) is a safe and feasible minimally invasive technique. This meta-analysis shows very low rates of mortality, stroke, and bleeding, with no conversions, highlighting TE-AVR

Keywords:

endoscopic aortic valve replacement endoscopic cardiac surgery minimally invasive cardiac surgery

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Last Updated: Feb 28, 2026

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Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

Published on: December 11, 2017

Area of Science:

Cardiovascular Surgery
Minimally Invasive Procedures
Medical Technology Assessment

Background:

Totally endoscopic aortic valve replacement (TE-AVR) offers potential benefits over traditional sternotomy.
Evidence for the safety and feasibility of the totally endoscopic approach is limited.
This meta-analysis systematically evaluates perioperative outcomes of TE-AVR.

Purpose of the Study:

To assess the safety and feasibility of TE-AVR.
To aggregate and analyze perioperative outcomes including mortality, stroke, conversion, bleeding, paravalvular leak (PVL), and atrial fibrillation (AF).

Main Methods:

Systematic literature search of PubMed, Embase, and Cochrane Library following PRISMA 2020 guidelines.
Inclusion of observational studies and randomized controlled trials reporting TE-AVR outcomes.
Single-arm proportion meta-analysis with leave-one-out sensitivity analyses.

Main Results:

Pooled analysis of 11 studies (1135 patients) showed 0.00% perioperative mortality and 0.69% stroke incidence.
No conversions to sternotomy (0.00%) were reported; bleeding reintervention was 1.75% and PVL was 1.24%.
Atrial fibrillation incidence was 10.54%, with significant heterogeneity noted in reporting.

Conclusions:

TE-AVR is a safe and feasible technique with very low mortality, stroke, and bleeding rates.
The absence of conversions indicates high technical reliability.
Future studies with standardized AF definitions are needed; TE-AVR shows promise for improved recovery and aesthetics.