Comparative Photopic and Mesopic Visual Performance of Enhanced Monofocal Versus Non-Diffractive Extended...

Area of Science:

• Ophthalmology
• Biomedical Engineering
• Optics

Background:

• Enhanced monofocal and extended depth-of-focus (EDoF) intraocular lenses (IOLs) are designed to improve intermediate vision and contrast sensitivity.
• Limited comparative data exists for these IOLs under photopic and mesopic conditions.

Purpose of the Study:

• To prospectively compare the visual performance of two enhanced monofocal IOLs (Tecnis Eyhance, ISOPure) and one non-diffractive EDoF IOL (AcrySof IQ Vivity).

Main Methods:

• Sixty patients received bilateral cataract surgery with one of the three IOL types (n=20 per group).
• Visual acuities (distance, intermediate, near) were measured under photopic and mesopic conditions one month postoperatively.
• Photopic defocus curves and contrast sensitivity were assessed.

Main Results:

• AcrySof IQ Vivity demonstrated superior uncorrected distance, distance-corrected intermediate, and distance-corrected near visual acuity under photopic conditions.
• Vivity also showed better intermediate and near visual acuity under mesopic conditions, while distance acuity was comparable across groups.
• Contrast sensitivity was similar for all IOLs in both lighting conditions.

Conclusions:

• The non-diffractive EDoF AcrySof IQ Vivity IOL provides a wider functional depth-of-focus without compromising contrast sensitivity.
• Tecnis Eyhance and ISOPure IOLs offer comparable performance with good distance vision and moderate depth-of-focus extension.
• All three IOLs maintained contrast sensitivity comparable to standard monofocal IOLs, with no clinically significant contrast penalty.