Related Experiment Video
Updated: Jun 16, 2026

05:46
Correction of Presbyopia by Monocular Bi-Aspheric Ablation Profile
Published on: September 20, 2024
Adaptive-Optics-Based Simulation of Astigmatism Effects on Visual Acuity with Enhanced Monofocal Intraocular Lenses
César Albarrán-Diego1, María García-Montero2, Inas Baoud Ould Haddi3
1Department of Optics, Optometry and Vision Science, Universitat de València, Burjassot, Spain.
Summary
Visual acuity declines with increasing astigmatism for enhanced monofocal intraocular lenses (IOLs). Astigmatism magnitude is the primary factor, with axis orientation and pupil size also affecting intermediate vision, but IOLs show similar tolerance.
Area of Science:
- Ophthalmology
- Optics
- Biomedical Engineering
Background:
- Cataract surgery often involves intraocular lens (IOL) implantation.
- Enhanced monofocal IOLs aim to improve visual acuity across various distances.
- Astigmatism can impact visual outcomes after IOL surgery.
Purpose of the Study:
- To evaluate how astigmatism magnitude and axis orientation affect visual acuity with two enhanced monofocal IOLs.
- To assess the influence of pupil size on visual performance with these IOLs.
- To compare the astigmatic tolerance of RayOne EMV and Tecnis Eyhance IOLs using adaptive optics simulation.
Main Methods:
- A prospective study involving 24 participants aged 50-69 years.
- Adaptive optics simulation was used to model two enhanced monofocal IOLs (RayOne EMV, Tecnis Eyhance).
- Induced hyperopic astigmatism was applied, and visual acuity was measured at distance and intermediate ranges under various pupil sizes.
Main Results:
- Visual acuity degraded with increasing astigmatism magnitude at both distance and intermediate ranges.
- Astigmatism axis orientation and pupil diameter significantly modulated intermediate visual acuity.
- No significant differences in visual acuity degradation or astigmatic tolerance were found between the two IOLs.
Conclusions:
- Visual acuity deteriorates with increasing hyperopic astigmatism for both tested enhanced monofocal IOLs.
- Cylinder magnitude is the primary determinant of visual acuity loss.
- Astigmatic tolerance is comparable between RayOne EMV and Tecnis Eyhance IOLs.
Related Concept Videos
Focusing of Light in the Eye
Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...
Angle Closure Glaucoma: Treatment
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Open Angle Glaucoma: Treatment
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
Glaucoma: Overview
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

