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Related Experiment Video

Updated: Feb 28, 2026

CT-guided Preoperative Localization of Pulmonary Nodules Using a Glucose Test and Tissue Adhesive
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Rationale for the Nodule Management Protocol of the Australian National Lung Cancer Screening Program.

Mark W McCusker1,2, Samantha Ellis3,4, Diane M Pascoe1,2

  • 1Department of Radiology, Royal Melbourne Hospital, Melbourne, Victoria, Australia.

Journal of Medical Imaging and Radiation Oncology
|February 27, 2026
PubMed
Summary

Australia is establishing a National Lung Cancer Screening Program (NLSCP) using low-dose computed tomography (LDCT) for early lung cancer detection in high-risk individuals. The program utilizes the PanCan model and Lung-RADS for risk assessment and nodule management.

Keywords:
chest CTlow‐dose CTlung cancerprotocolpulmonary nodulesscreening

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Area of Science:

  • Oncology
  • Radiology
  • Public Health

Background:

  • Lung cancer remains a significant health burden globally.
  • Early detection through screening improves patient outcomes and survival rates.
  • Asymptomatic high-risk individuals benefit most from targeted screening programs.

Purpose of the Study:

  • To outline the rationale and development of the Australian National Lung Cancer Screening Program (NLSCP) Nodule Management Protocol.
  • To detail the integration of key recommendations from the Australian Medical Services Advisory Committee (MSAC) into a practical screening protocol.
  • To adapt international best practices for lung cancer screening to the Australian healthcare context.

Main Methods:

  • Development of a bespoke protocol based on MSAC recommendations.
  • Incorporation of biennial screening intervals.
  • Integration of the PanCan risk prediction model for baseline LDCT interpretation.
  • Adoption of the Lung-RADS (Lung Imaging Reporting and Data System) for follow-up LDCT reporting.

Main Results:

  • A comprehensive Nodule Management Protocol for the Australian NLSCP has been established.
  • The protocol standardizes the use of LDCT, PanCan model, and Lung-RADS for lung cancer screening.
  • Adaptations ensure the protocol is suitable for the Australian population and healthcare system.

Conclusions:

  • The developed protocol provides a framework for the Australian NLSCP, enhancing early lung cancer detection.
  • Standardized risk assessment and nodule management are crucial for effective lung cancer screening.
  • This initiative represents a significant step towards reducing lung cancer mortality in Australia.