Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

5.9K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
5.9K
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

1.4K
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
1.4K
Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

4.0K
The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
4.0K
Infection01:20

Infection

13.1K
When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
13.1K
Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

14.2K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
14.2K
Inflammatory Response I: Vascular and Cellular01:30

Inflammatory Response I: Vascular and Cellular

17.4K
The inflammatory response is the body's defense against infection, injury, or irritation from bacteria, trauma, toxins, or heat. Inflammation helps locate and destroy pathogens and remove damaged tissue elements to heal the body. During this initial phase, fluid, blood products, and nutrients migrate to the injured area, resulting in redness, heat, swelling, ache, and loss of function. Moreover, signs of systemic inflammation include fever, increased WBC count, malaise, anorexia, nausea,...
17.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Skeletal Stilbenolignan Enantiomers and Flavonoid Derivatives Against Depression in Mice from <i>Dracaena cochinchinensis</i> Exudates.

International journal of molecular sciences·2026
Same author

Electron scattering on carbon monoxide: An optimization of target molecular orbitals.

The Journal of chemical physics·2026
Same author

Chizhiaroterpenoids A-C: Benzofused Rearranged Lanostane-Type Triterpenoids from <i>Ganoderma lucidum</i>.

Organic letters·2025
Same author

Stepped {110} Facet-Enriched Ga<sup>3+</sup>-Doped SrTiO<sub>3</sub> Crystal Nanoparticles for Enhanced Photocatalytic Overall Water Splitting Reaction.

Inorganic chemistry·2025
Same author

Commiphoralactone A: A Hetero-Hybridized Sesquiterpene from <i>Commiphora</i> Sap against Depression That Targets Neuroflammation <i>In Vivo</i>.

Organic letters·2025
Same author

Homologous Ladder Cyclohexasilanes.

Angewandte Chemie (International ed. in English)·2025

Related Experiment Video

Updated: Mar 3, 2026

Imaging CD4 T Cell Interstitial Migration in the Inflamed Dermis
11:28

Imaging CD4 T Cell Interstitial Migration in the Inflamed Dermis

Published on: March 25, 2016

11.3K

Diverging Global Patterns and Temporal Trends in Inflammatory and Infectious Skin Diseases.

Qingrong Ni1, Lin Xia2, Xiaoying Yuan1

  • 1Department of Dermatology, Air Force Medical Center, Fourth Military Medical University, Beijing, 100142, People's Republic of China.

Clinical, Cosmetic and Investigational Dermatology
|March 2, 2026
PubMed
Summary

Skin diseases are a major global health burden, causing significant disability. This study tracked trends from 1990-2021, revealing disparities and highlighting the need for better public health prioritization.

Keywords:
dermatologyglobal disease burdeninfectious skin diseasesinflammatory skin diseases

More Related Videos

Preparation of Single-cell Suspensions for Cytofluorimetric Analysis from Different Mouse Skin Regions
05:58

Preparation of Single-cell Suspensions for Cytofluorimetric Analysis from Different Mouse Skin Regions

Published on: April 20, 2016

19.6K
Infecting Mice with Malassezia spp. to Study the Fungus-Host Interaction
06:19

Infecting Mice with Malassezia spp. to Study the Fungus-Host Interaction

Published on: November 6, 2019

14.6K

Related Experiment Videos

Last Updated: Mar 3, 2026

Imaging CD4 T Cell Interstitial Migration in the Inflamed Dermis
11:28

Imaging CD4 T Cell Interstitial Migration in the Inflamed Dermis

Published on: March 25, 2016

11.3K
Preparation of Single-cell Suspensions for Cytofluorimetric Analysis from Different Mouse Skin Regions
05:58

Preparation of Single-cell Suspensions for Cytofluorimetric Analysis from Different Mouse Skin Regions

Published on: April 20, 2016

19.6K
Infecting Mice with Malassezia spp. to Study the Fungus-Host Interaction
06:19

Infecting Mice with Malassezia spp. to Study the Fungus-Host Interaction

Published on: November 6, 2019

14.6K

Area of Science:

  • Global health epidemiology
  • Dermatology
  • Public health policy

Background:

  • Skin and subcutaneous diseases are a leading cause of non-fatal health burden globally.
  • Despite high prevalence and impact on quality of life, these conditions are underprioritized in public health.

Purpose of the Study:

  • To examine long-term global trends in the burden of inflammatory and infectious skin diseases.
  • To investigate regional disparities in skin disease burden from 1990 to 2021.

Main Methods:

  • Cross-sectional analysis of data from the Global Burden of Disease (GBD) Study 2021.
  • Assessment of age-standardized incidence rates, years lived with disability (YLDs), and average annual percentage change (AAPC).
  • Analysis across 204 countries, 21 global regions, and all age groups.

Main Results:

  • In 2021, skin diseases were the eighth leading cause of YLDs worldwide.
  • Inflammatory skin diseases showed modest increases in incidence and YLDs (1990-2021).
  • Infectious skin diseases had a greater incidence rise, while YLDs slightly declined; burden varied by sociodemographic index and age, with highest impact in those under 20.

Conclusions:

  • Inflammatory and infectious skin diseases have distinct global trends and disproportionate burdens.
  • Findings emphasize the need for context-specific prevention and equitable health service delivery.
  • Greater policy prioritization of skin disease management is crucial for global and national health agendas.