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Published on: March 4, 2014
Non-sensorimotor symptoms in chronic inflammatory demyelinating polyneuropathy
Fabian Klostermann1,2, Oliver L Steiner3,4,5
1Department of Neurology, Motor and Cognition Group, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Campus Benjamin Franklin (CBF), Hindenburgdamm 30, 12203, Berlin, Germany. fabian.klostermann@charite.de.
Abstract:
Chronic inflammatory demyelinating polyneuropathy (CIDP) is defined as a dysimmune disorder of the peripheral nervous system (PNS) resulting in sensorimotor deficits. However, an increasing body of data suggests that CIDP also goes along with features, such as autonomic, circadian, fatigue, mood, and subtle cognitive dysfunctions. Some of these non-sensorimotor symptoms (NSMS) challenge the concept of an exclusive PNS disease. Pragmatically, the high prevalence of NSMS calls for a more holistic disease assessment and surveillance to achieve optimal therapeutic results.
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