Related Experiment Video
Updated: May 2, 2026

Coronary Progenitor Cells and Soluble Biomarkers in Cardiovascular Prognosis after Coronary Angioplasty
Published on: January 28, 2020
Prognosis biomarkers in MOGAD: What can we learn from observational studies?
B Lemarchant1, P Cleuziou2, S Rogeau3
1Centre de compétence maladies Rares (CCMR) pour les Maladies Rares du cerveau et de la moelle (MIRCEM) of Lille, CHU of Lille, Lille, France; Centre de ressources et compétences pour la SEP (CRC-SEP) de Lille, Lille, France; University of Lille, INSERM U1172 team TREAT, Lille, France; Department of Neuroradiology, CHU of Lille, Lille, France.
Abstract:
Myelin oligodendrocyte glycoprotein (MOG) antibody-associated disease (MOGAD) is a recently defined inflammatory demyelinating disease of the central nervous system, affecting both children and adults. MOGAD pathologically differs from multiple sclerosis and neuromyelitis optica spectrum disorder (NMOSD). In this review, observational studies highlight an often-monophasic disease without an evident progression course and suggest, for a better recovery, the need for early and active anti-inflammatory action during attacks. We aim to specify hallmarks for the risk of relapse and long-term prognosis. Innovative clinical, biological and imaging biomarkers have been tested. Questions to be resolved are the optimal management of each attack and the definition of the window of opportunity to treat, looking to modify the risk of a potential relapsing disease course, with cumulative disability.
Related Concept Videos
Observational Studies
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One...
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Pharmacogenomics: Identification of New Drug Targets
Cancer Survival Analysis

