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Cytologic Features Across Molecular Subtypes of Small Cell Lung Carcinoma: Classical Uniformity With Exceptions in

Kai Mizoguchi1, Yuki Teramoto1, Masahiro Hirata1

  • 1Department of Diagnostic Pathology, Kyoto University Hospital, Kyoto, Japan.

Cytopathology : Official Journal of the British Society for Clinical Cytology
|March 6, 2026
PubMed
Summary

Cytomorphology is mostly consistent across small cell lung carcinoma (SCLC) molecular subtypes. However, a few POU2F3-positive SCLC subtypes may show non-classical features, requiring careful diagnosis to avoid misclassification.

Keywords:
POU2F3cytodiagnosisimmunohistochemistrymolecular subtypesmall cell lung carcinomatranscription factors

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