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Related Concept Videos

Chronic Pancreatitis II: Collaborative Care01:29

Chronic Pancreatitis II: Collaborative Care

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The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
452
Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

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The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
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Acute Pancreatitis II: Clinical Manifestations and Management01:30

Acute Pancreatitis II: Clinical Manifestations and Management

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Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
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Acute Pancreatitis I: Introduction01:27

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Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
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Pancreatic Juice and Secretion01:26

Pancreatic Juice and Secretion

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Pancreatic juice is a clear fluid produced by the pancreas, containing water, salts, sodium bicarbonate, and enzymes vital for digestion in the small intestine. It helps break down large molecules, facilitating nutrient absorption.
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Cells and Secretions of the Pancreas01:16

Cells and Secretions of the Pancreas

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The pancreas, a vital organ within the abdominal cavity, plays dual roles in the digestive and endocrine systems, collaborating with exocrine and endocrine cells to maintain optimal digestion and blood sugar levels.
Exocrine function is carried out by acinar cells, organized into clusters known as acini. These cells contribute to digestion by releasing substantial quantities of enzyme-rich, alkaline digestive juices.
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Related Experiment Video

Updated: Mar 12, 2026

Development and Validation of a Methodology for Establishing Obese Rat Models with Typical Fatty Pancreas
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Development and Validation of a Methodology for Establishing Obese Rat Models with Typical Fatty Pancreas

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Fatty pancreas: Current insights and future perspectives.

Hussein Hassan Okasha1, Abdullah Zuhair Alyouzbaki2, Nadeem Tehami3

  • 1Division of Gastroenterology and Hepatology, Department of Internal Medicine, Kasr Al-Aini School of Medicine, Cairo University, Cairo 11562, Egypt. okasha.hussein@gmail.com.

World Journal of Methodology
|March 11, 2026
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Non-alcoholic fatty pancreatic disease (NAFPD) involves pancreas fat accumulation, distinct from liver conditions like MASLD. Understanding NAFPD

Keywords:
Early diagnosisMetabolic dysfunction-associated steatotic liver diseaseMetabolic syndromeNon-alcoholic fatty pancreas diseaseObesity

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A Simple and Rapid Method for Simultaneous Isolation of Primary Islets and Primary Pancreatic Acinar Cells from Mice
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Stabilized Longitudinal In Vivo Cellular-Level Visualization of the Pancreas in a Murine Model with a Pancreatic Intravital Imaging Window
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A Simple and Rapid Method for Simultaneous Isolation of Primary Islets and Primary Pancreatic Acinar Cells from Mice
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A Simple and Rapid Method for Simultaneous Isolation of Primary Islets and Primary Pancreatic Acinar Cells from Mice

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Stabilized Longitudinal In Vivo Cellular-Level Visualization of the Pancreas in a Murine Model with a Pancreatic Intravital Imaging Window
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Area of Science:

  • Endocrinology and Metabolism
  • Gastroenterology
  • Pathology

Background:

  • Rising global obesity rates correlate with emerging conditions like non-alcoholic fatty pancreatic disease (NAFPD).
  • NAFPD is characterized by pancreatic fat accumulation in individuals with minimal alcohol consumption.
  • The pathogenesis of NAFPD is not well understood, with terms like pancreatic steatosis being used interchangeably.

Purpose of the Study:

  • To review recent advancements in understanding non-alcoholic fatty pancreatic disease (NAFPD).
  • To highlight challenges in NAFPD diagnosis, risk factor identification, and pathogenesis.
  • To underscore the growing clinical and research interest in NAFPD, paralleling that of MASLD.

Main Methods:

  • Literature review of recent advancements in NAFPD research.
  • Analysis of challenges in precise pancreatic fat quantification.
  • Synthesis of current understanding regarding NAFPD risk factors and clinical implications.

Main Results:

  • NAFPD is an emerging condition linked to obesity, mirroring liver fat accumulation in MASLD.
  • Precise quantification of pancreatic fat remains a significant diagnostic challenge.
  • Current research efforts are focused on elucidating NAFPD's pathogenesis and clinical associations.

Conclusions:

  • Further large-scale cohort and multicenter studies are crucial for advancing NAFPD knowledge.
  • Enhanced understanding is expected to improve early diagnosis and treatment strategies for NAFPD.
  • Exploring NAFPD's clinical associations will provide a more comprehensive view of its impact.